Free shipping on all orders over $ 500

Fluoxetine

Cat. No. M14577

All AbMole products are for research use only, cannot be used for human consumption.

Fluoxetine Structure
Synonym:

LY-110140 free base

Size Price Availability Quantity
100mg USD 80 In stock
500mg USD 180 In stock
1g USD 240 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Fluoxetine (LY-110140 free base) is a selective serotonin reuptake inhibitor (SSRI) class used for antidepressant research. Fluoxetine blocks the downregulation of cell proliferation resulting from inescapable shock (IS) of hippocampal cell. Fluoxetine increases the number of newborn cells in the dentate gyrus of the hippocampus of adult rat. Fluoxetine also increases the number of proliferating cells in the prelimbic cortex.

Product Citations
Chemical Information
Molecular Weight 309.33
Formula C17H18F3NO
CAS Number 54910-89-3
Form Liquid
Solubility (25°C) DMSO 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Ahmed Barakat, et al. Uses of fluoxetine in nociceptive pain management: A literature overview

[2] Jing-Wen Wang, et al. J Neurosci. Chronic fluoxetine stimulates maturation and synaptic plasticity of adult-born hippocampal granule cells

[3] Masafumi Kodama, et al. Biol Psychiatry. Chronic olanzapine or fluoxetine administration increases cell proliferation in hippocampus and prefrontal cortex of adult rat

[4] Jessica E Malberg, et al. Neuropsychopharmacology. Cell proliferation in adult hippocampus is decreased by inescapable stress: reversal by fluoxetine treatment

[5] Frank P Bymaster, et al. Psychopharmacology (Berl). Fluoxetine, but not other selective serotonin uptake inhibitors, increases norepinephrine and dopamine extracellular levels in prefrontal cortex

[6] W Zhang, et al. Neuropsychopharmacology. Synergistic effects of olanzapine and other antipsychotic agents in combination with fluoxetine on norepinephrine and dopamine release in rat prefrontal cortex

[7] P Benfield, et al. Fluoxetine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in depressive illness

Related 5-HT Receptor Products
Granisetron hydrochloride

Granisetron hydrochloride is a potent and selective 5-HT3 receptor antagonist that possesses potent antiemetic activity.

Sumatriptan succinate

Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for the research of migraine headache.

Vortioxetine hydrobromide

Vortioxetine hydrobromide (Lu AA21004) is a 5-HT3, 5-HT7 and 5-HT1D receptor antagonist, a 5-HT1B receptor partial agonist, a 5-HT1A receptor agonist and a 5-HT transporter (5-HTT) inhibitor in vitro.

Prucalopride

Prucalopride is a potent, selective and specific serotonin 5-HT4 receptor agonist with enterokinetic properties.

(1S-cis)-Milnacipran Hydrochloride

(1S-cis)-Milnacipran hydrochloride is a selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia.

  Catalog
Abmole Inhibitor Catalog




Keywords: Fluoxetine, LY-110140 free base supplier, 5-HT Receptor, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.