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FLTX1

Cat. No. M45333

All AbMole products are for research use only, cannot be used for human consumption.

FLTX1 Structure
Size Price Availability Quantity
1mg USD 120 In stock
5mg USD 270 In stock
10mg USD 420 In stock
25mg USD 720 In stock
50mg USD 980 In stock
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Quality Control & Documentation
Biological Activity

FLTX1 is a fluorescent tamoxifen derivative that specifically labels intracellular tamoxifen binding sites (estrogen receptors) under permeabilizing and non-permeabilizing conditions. In addition, FLTX1 exhibits potent anti-estrogenic activity of Tamoxifen in breast cancer cells.FLTX1 lacks estrogenic agonism in the uterus.

Chemical Information
Molecular Weight 520.58
Formula C31H28N4O4
CAS Number 1481401-71-1
Form Solid
Solubility (25°C) DMSO 25 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Mario Díaz, et al. Int J Mol Sci. FLTX2: A Novel Tamoxifen Derivative Endowed with Antiestrogenic, Fluorescent, and Photosensitizer Properties

[2] F Lahoz, et al. Spectrochim Acta A Mol Biomol Spectrosc. FRET mechanism between a fluorescent breast-cancer drug and photodynamic therapy sensitizers

[3] Araceli Morales, et al. Methods Mol Biol. Colocalization of Estrogen Receptors with the Fluorescent Tamoxifen Derivative, FLTX1, Analyzed by Confocal Microscopy

[4] Jorge Marrero-Alonso, et al. Eur J Pharm Biopharm. Unique SERM-like properties of the novel fluorescent tamoxifen derivative FLTX1

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Keywords: FLTX1 supplier, Estrogen Receptor, inhibitors, activators

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