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Flemiphilippinin D (Kushenol E) is a non-competitive indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an IC50 of 7.7 µM and a Ki of 9.5 µM. Flemiphilippinin D (Kushenol E) is a flavonoid isolated from Sophora flavescens, it has anti-tumor activity.
| Molecular Weight | 424.49 |
| Formula | C25H28O6 |
| CAS Number | 99119-72-9 |
| Solubility (25°C) | Soluble in DMSO Soluble in Chloroform |
| Storage | 4°C, protect from light, dry, sealed |
[1] Hua Li, et al. Zhongguo Zhong Yao Za Zhi. [Flavonoids from roots of Flemingia philippinensis]
| Related IDO Products |
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| IDO-IN-2 (NLG-919 Analogue)
NLG919 is a potent IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor with Ki/EC50 of 7 nM/75 nM. |
| IDO5L
IDO5L is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 67 nM. |
| Coptisine
Coptisine, an alkaloid isolated from Coptis, is an effective non-competitive IDO inhibitor with Ki value of 5.8 μM and IC50 value of 6.3 μM. |
| Coptisine chloride
Coptisine chloride is an effective and non-competitive IDO inhibitor with Ki value of 5.8 μM and IC50 value of 6.3 μM. Coptisine chloride is an effective H1N1 neuraminidase (NA-1) inhibitor with IC50 of 104.6 μg/mL, which can be used for influenza A virus (H1N1) infection. |
| Coptisine-Sulfate
Coptisine Sulfate is an alkaloid isolated from coptis coptidis. It is an effective non-competitive IDO inhibitor with Ki value of 5.8 μM and IC50 value of 6.3 μM. |
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