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Flavokawain B

Cat. No. M10757

All AbMole products are for research use only, cannot be used for human consumption.

Flavokawain B Structure
Synonym:

Flavokavain B

Size Price Availability Quantity
5mg USD 200 In stock
10mg USD 310 In stock
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Quality Control & Documentation
Biological Activity

Flavokawain B (Flavokavain B) is a chalcone isolated from the root extract of kava drunken pepper and is an effective apoptotic inducer that inhibits the growth of various cancer cell lines. (Flavokavain B) has strong anti-angiogenic activity. (Flavokavain B) inhibits the migration and vascular formation of human brain endothelial cells (HUVEC) at very low non-toxic concentrations.

Chemical Information
Molecular Weight 284.31
Formula C17H16O4
CAS Number 1775-97-9
Solubility (25°C) DMSO ≥ 5 mg/mL
Storage 4°C,protect from light ,dry ,sealed
References

[1] Wu Luo, et al. Acta Pharmacol Sin. Flavokawain B alleviates LPS-induced acute lung injury via targeting myeloid differentiation factor 2

[2] Rong Hua, et al. J BUON. Antitumor effects of flavokawain-B flavonoid in gemcitabine-resistant lung cancer cells are mediated via mitochondrial-mediated apoptosis, ROS production, cell migration and cell invasion inhibition and blocking of PI3K/AKT Signaling pathway

[3] A Palko-Łabuz, et al. Hum Exp Toxicol. Cyclization of flavokawain B reduces its activity against human colon cancer cells

[4] Jiwei Wang, et al. Autophagy. Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy

[5] Yan-Lai Tang, et al. Leuk Lymphoma. Flavokawain B inhibits the growth of acute lymphoblastic leukemia cells via p53 and caspase-dependent mechanisms

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Keywords: Flavokawain B, Flavokavain B supplier, Apoptosis, inhibitors, activators

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