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Fexinidazole

Cat. No. M10339

All AbMole products are for research use only, cannot be used for human consumption.

Fexinidazole Structure
Synonym:

Hoe-239

Size Price Availability Quantity
5mg USD 80 In stock
10mg USD 130 In stock
50mg USD 360 In stock
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Quality Control & Documentation
Biological Activity

Fexinidazole (also known as Hoe-239) is an orally active, potent antiparasitic agent. Fexinidazole shows trypanocidal activity against T. brucei subspecies and strains with IC50s of 0.7-3.3 μM (0.2-0.9 μg/ml).

Chemical Information
Molecular Weight 279.31
Formula C12H13N3O3S
CAS Number 59729-37-2
Solubility (25°C) DMSO ≥ 30 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Francois Chappuis. Lancet. Oral fexinidazole for human African trypanosomiasis

[2] Susan Wyllie, et al. Sci Transl Med. The anti-trypanosome drυg fexinidazole shows potential for treating visceral leishmaniasis

[3] Marcel Kaiser, et al. Antimicrob Agents Chemother. Antitrypanosomal activity of fexinidazole, a new oral nitroimidazole drυg candidate for treatment of sleeping sickness

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Keywords: Fexinidazole, Hoe-239 supplier, Anti-infection, inhibitors, activators

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