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Fasitibant chloride hydrochloride

Cat. No. M30761

All AbMole products are for research use only, cannot be used for human consumption.

Fasitibant chloride hydrochloride Structure
Synonym:

MEN16132

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Quality Control & Documentation
Biological Activity

Fasitibant chloride hydrochloride (MEN16132) is a potent, selective, high affinity, and long-lasting nonpeptide bradykinin B2 (BK2) receptor antagonist. Fasitibant chloride hydrochloride has proinflammatory effects and can be used for the research of osteoarthritis and rheumatoid arthritis.

Chemical Information
Molecular Weight 836.7
Formula C36H50Cl4N6O6S
CAS Number 869880-33-1
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Kenneth J Broadley, et al. J Pharmacol Exp Ther. Bradykinin-induced lung inflammation and bronchoconstriction: role in parainfluenze-3 virus-induced inflammation and airway hyperreactivity

[2] Cecilia Cialdai, et al. J Pharmacol Exp Ther. Effect of Intra-articular 4-(S)-amino-5-(4-{4-[2,4-dichloro-3-(2,4-dimethyl-8-quinolyloxymethyl)phenylsulfonamido]-tetrahydro-2H-4-pyranylcarbonyl} piperazino)-5-oxopentyl](trimethyl)ammonium chloride hydrochloride (MEN16132), a kinin B2 receptor antagoni䲧癐Ỵ癑㧀癏羹瘸盋晸ƘƌƘÐ�瘺嶁瘶Ѐ瑖抩䀹⹜ࢹƘÐèࢹ彿抪奋抪巫抪䬄ࢹ

[3] Paola Cucchi, et al. Eur J Pharmacol. MEN16132, a novel potent and selective nonpeptide antagonist for the human bradykinin B2 receptor. In vitro pharmacology and molecular characterization

[4] Claudio Valenti, et al. J Pharmacol Exp Ther. MEN16132, a novel potent and selective nonpeptide kinin B2 receptor antagonist: in vivo activity on bradykinin-induced bronchoconstriction and nasal mucosa microvascular leakage in anesthetized guinea pigs

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Keywords: Fasitibant chloride hydrochloride, MEN16132 supplier, Bradykinin Receptor, inhibitors, activators

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