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Farletuzumab MMAE is an antibody-drug conjugate (ADC), consisting of the humanized anti-human folate receptor alpha (FRA) antibody Farletuzumab conjugated to MMAE.
Immobilized human FRα at 2 ug/mL can bind farletuzumab-MMAE, EC50=0.009171 ug/mL.
The drug-to-antibody ratio (DAR) of the Farletuzumab-MMAE is 3.6.
| Molecular Weight | 150620 |
| Storage | Store at ≤ -20℃ for 24 months. Avoid repeated freeze-thaw cycles. |
[1] Mariana Scaranti, et al. Nat Rev Clin Oncol. Exploiting the folate receptor α in oncology
[4] Anish Thomas, et al. Lung Cancer. Farletuzumab in lung cancer
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