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FAP Ligand 1

Cat. No. M42870

All AbMole products are for research use only, cannot be used for human consumption.

FAP Ligand 1 Structure

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Biological Activity

FAP Ligand 1 (FL), a high-affinity FAP small-molecule ligand, is used to target attached drugs to FAP-expressing fibroblasts and can be used in radiation imaging studies of targeted cancers.

Chemical Information
Molecular Weight 337.32
Formula C15H17F2N5O2
CAS Number 2230625-76-8
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Junedh M Amrute et al. Res Sq. Targeting Immune-Fibroblast Crosstalk in Myocardial Infarction and Cardiac Fibrosis

[2] Inja Waldhauer et al. MAbs. Simlukafusp alfa (FAP-IL2v) immunocytokine is a versatile combination partner for cancer immunotherapy

[3] Muyue Yang et al. Bioact Mater. The application of nanoparticles in cancer immunotherapy: Targeting tumor microenvironment

[4] Christine Feig et al. Proc Natl Acad Sci U S A. Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer

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Keywords: FAP Ligand 1 supplier, inhibitors, activators

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