Free shipping on all orders over $ 500

Facinicline hydrochloride

Cat. No. M30469

All AbMole products are for research use only, cannot be used for human consumption.

Facinicline hydrochloride Structure
Synonym:

RG3487 hydrochloride

Price and Availability

For this product's availability, delivery time and price, please email inquiry@abmole.com directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

Facinicline hydrochloride (RG3487 hydrochloride) is an orally active nicotinic α7 receptor partial agonist, with a Ki of 6 nM for α7 human nAChR. Facinicline hydrochloride (RG3487 hydrochloride) improves cognition and sensorimotor gating in rodents. Facinicline hydrochloride (RG3487 hydrochloride) shows high affinity (antagonist) to 5-HT3Rs with a Ki value of 1.2 nM.

Chemical Information
Molecular Weight 306.79
Formula C15H19ClN4O
CAS Number 677305-02-1
Form Solid
Solubility (25°C) DMSO 125 mg/mL (ultrasonic)
Water 100 mg/mL (ultrasonic)
Storage 4°C, dry, sealed
References

[1] Semahegn Asemare, et al. J Fluoresc. Ground and Excited State Dipole Moments of Metformin Hydrochloride using Solvatochromic Effects and Density Functional Theory

[2] Ha Jung Lee, et al. Cells. Nalfurafine Hydrochloride, a κ-Opioid Receptor Agonist, Induces Melanophagy via PKA Inhibition in B16F1 Cells

[3] Chuangchuang Xu, et al. Org Biomol Chem. Metal-free and regiospecific synthesis of 3-arylindoles

[4] No authors listed. Carteolol

[5] S Groszkowski, et al. Pol J Pharmacol Pharm. 1-Haloacylpiperazines

Related AChR/AChE Products
VU 0255035

VU 0255035 is a highly selective M1 muscarinic acetylcholine receptor (mAChR) antagonist (Ki = 14.87 nM).

Fesoterodine fumarate

Fesoterodine fumarate (Toviaz) is a novel muscarinic receptor antagonist.

SVT-40776

SVT-40776 is a novel M3 muscarinic receptor antagonist.

Aniracetam

Aniracetam is a compound that promotes intellectual development and neuroprotection.

Biperiden hydrochloride

Biperiden (KL 373) hydrochloride is a non-selective muscarinic receptor antagonist that competitively binds to M1 muscarinic receptors, thereby inhibiting acetylcholine and enhancing dopamine signaling in the central nervous system.

  Catalog
Abmole Inhibitor Catalog




Keywords: Facinicline hydrochloride, RG3487 hydrochloride supplier, AChR/AChE, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.