All AbMole products are for research use only, cannot be used for human consumption.
Ezatiostat inhibits the enzyme, glutathione S-transferase P1-1, GSTP1-1 is a key regulatory protein that can signal the cell to either make more blood elements or if the cell is cancerous to die.This inhibition induces a dissociation of GST P1-1 from its complex with c-jun N-terminal kinase (JNK)/c-Jun and activates signaling pathways that lead to cell proliferation and differentiation of normal hematopoietic cells and apoptosis of malignant cells.It has shown significant clinical activityof ezatiostat, a glutathione S-transferase P1-1 inhibitor in clinical development for the treatment of low- to intermediate-risk MDS.
| Molecular Weight | 529.65 |
| Formula | C27H35N3O6S |
| CAS Number | 168682-53-9 |
| Solubility (25°C) | DMSO 80 mg/mL Ethanol 80 mg/mL |
| Storage | -20°C, dry, sealed |
| Related Apoptosis Products |
|---|
| 23-Hydroxybetulinic acid
23-Hydroxybetulinic acid is a novel anticancer substance. |
| TH-302 (Evofosfamide)
TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| Aloperine
Aloperine is exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties. |
| Ibandronate sodium
Ibandronate sodium is a potent nitrogen-containing bisphosphonate that can be used in studies related to osteoporosis. |
| 5-Aminolevulinic acid hydrochloride
5-Aminolevulinic acid hydrochloride is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
