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Ezabenlimab

Cat. No. M25035

All AbMole products are for research use only, cannot be used for human consumption.

Ezabenlimab Structure
Synonym:

BI-754091

Price and Availability

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Quality Control & Documentation
Biological Activity

Ezabenlimab (BI-754091) is an anti-PD-1 mAb with binding constant Kd value of 6 nM (CHO cells). Ezabenlimab blocks the interaction of PD-1 with PD-L1 and PD-L2. Ezabenlimab increases interferon-γ secretion in T cells, and inhibits tumor growth in vivo.

Chemical Information
CAS Number 2249882-54-8
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Markus Zettl, et al. Oncoimmunology. Combination of two novel blocking antibodies, anti-PD-1 antibody ezabenlimab (BI 754091) and anti-LAG-3 antibody BI 754111, leads to increased immune cell responses

[2] Mercedes Porosnicu, et al. Future Oncol. Phase I study of VSV-GP (BI 1831169) as monotherapy or combined with ezabenlimab in advanced and refractory solid tumors

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  Catalog
Abmole Inhibitor Catalog




Keywords: Ezabenlimab, BI-754091 supplier, PD-1/PD-L1, inhibitors, activators

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