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(S)-Selisistat

Cat. No. M30682

All AbMole products are for research use only, cannot be used for human consumption.

(S)-Selisistat Structure
Synonym:

(S)-EX-527

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Quality Control & Documentation
Biological Activity

(S)-Selisistat ((S)-EX-527) is a potent and selective SIRT1 inhibitor, with an IC50 of 98 nM.

Chemical Information
Molecular Weight 248.71
Formula C13H13ClN2O
CAS Number 848193-68-0
Form Solid
Solubility (25°C) DMSO ≥ 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Iram Khan Iqbal, et al. Autophagy. Hydrogen sulfide-induced GAPDH sulfhydration disrupts the CCAR2-SIRT1 interaction to initiate autophagy

[2] Xinfa Bai, et al. Mini Rev Med Chem. Small Molecules as SIRT Modulators

[3] J D Rollnik. Nervenarzt. [Huntington's disease]

[4] Pushkar Kulkarni, et al. Expert Opin Investig Drugs. Investigational drugs for the management of Huntington's disease: are we there yet?

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Keywords: (S)-Selisistat, (S)-EX-527 supplier, Sirtuin, inhibitors, activators

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