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Etoposide phosphate (BMY-40481) is a potent anti-cancer chemotherapy agent and a selective topoisomerase II inhibitor to prevent re-ligation of DNA strands. Etoposide phosphate is the phosphate ester prodrug of etoposide and is considered as active equivalent to Etoposide. Etoposide phosphate induces cell cycle arrest, apoptosis, and autophagy.
| Molecular Weight | 668.54 |
| CAS Number | 117091-64-2 |
| Solubility (25°C) | Water 90 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] K R Hande. Eur J Cancer. Etoposide: four decades of development of a topoisomerase II inhibitor
[4] L Schacter. Semin Oncol. Etoposide phosphate: what, why, where, and how?
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