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Etifoxine

Cat. No. M14218

All AbMole products are for research use only, cannot be used for human consumption.

Etifoxine Structure
Synonym:

HOE 36-801

Size Price Availability Quantity
5mg USD 74 In stock
10mg USD 100 In stock
50mg USD 280 In stock
100mg USD 420 In stock
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Quality Control & Documentation
Biological Activity

Etifoxine, a non-benzodiazepine GABAergic compound, is a positive allosteric modulator of α1β2γ2 and α1β3γ2 subunit-containing GABAA receptors. Etifoxine reveals anxiolytic and anticonvulsant properties in rodents.

Chemical Information
Molecular Weight 300.78
CAS Number 21715-46-8
Solubility (25°C) DMSO 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Eilam Palzur, et al. Etifoxine Restores Mitochondrial Oxidative Phosphorylation and Improves Cognitive Recovery Following Traumatic Brain Injury

[2] Hui Zhang, et al. TSPO ligand etifoxine attenuates LPS-induced cognitive dysfunction in mice

[3] Khalid S Ibrahim, et al. Etifoxine reverses weight gain and alters the colonic bacterial community in a mouse model of obesity

[4] Vesela Yu Kokova, et al. Etifoxine does not impair muscle tone and motor function in rats as assessed by in vivo and in vitro methods

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Keywords: Etifoxine, HOE 36-801 supplier, GABA Receptor, inhibitors, activators

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