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Etifoxine hydrochloride is a potentiator of GABAA receptor function in cultured neurons. Preferentially acts on β2 or β3 subunit-containing GABAA receptors. Exhibits anxiolytic activity in rodents and humans with no sedative, myorelaxant or mnesic side effects. Acts as a ligand of the translocator protein (TSPO); promotes axonal regeneration.
| Molecular Weight | 337.24 |
| Formula | C17H17ClN2O.HCl |
| CAS Number | 56776-32-0 |
| Form | Solid |
| Solubility (25°C) | DMSO 45 mg/mL Water 5 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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