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Ethyl potassium malonate

Cat. No. M20857

All AbMole products are for research use only, cannot be used for human consumption.

Ethyl potassium malonate Structure
Synonym:

Potassium 3-ethoxy-3-oxopropanoate, Malonic Acid Monoethyl Ester Potassium Salt

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Quality Control & Documentation
Biological Activity

Ethyl potassium malonate is used as a competitive inhibitor of the enzyme succinate dehydrogenase. It acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation and serves as an intermediate for the preparation of ethyl tert-butyl malonate.

Chemical Information
Molecular Weight 170.2
Formula C5H7KO4
CAS Number 6148-64-7
Solubility (25°C) Water 34.04 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Anastasia A Fesenko, et al. Org Biomol Chem. Synthesis of functionalized tetrahydro-1,3-diazepin-2-ones and 1-carbamoyl-1H-pyrroles via ring expansion and ring expansion/ring contraction of tetrahydropyrimidines

[2] Yu-Ping Liu, et al. Int J Mol Sci. Rapid synthesis of flavor compound 4-ethyloctanoic acid under microwave irradiation

[3] Jae Hoon Lee, et al. J Org Chem. The decarboxylative Blaise reaction

[4] A Ruoho, et al. Proc Natl Acad Sci U S A. Photoaffinity labeling of the ouabain-binding site on (Na+ plus K+) adenosinetriphosphatase

[5] G Clark. Stain Technol. Effects of additives on alum hematoxylin staining solutions

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Keywords: Ethyl potassium malonate, Potassium 3-ethoxy-3-oxopropanoate, Malonic Acid Monoethyl Ester Potassium Salt supplier, inhibitors, activators

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