All AbMole products are for research use only, cannot be used for human consumption.
Preincubation of the cells with the Na+ ionophore sodium ionophore III not only stimulated caffeate reduction, but completely abolished ATP synthesis. Addition of sodium ionophore III to cells in the steady state of caffeate reduction immediately dissipated the intracellular ATP level. Lactate-sulfate grown cells are insensitive to the Na+ ionophore, ETH2120. Sodium ionophore III ligand is a very effective receptor for the Eu3+ and Am3+ cations and can be considered as a potential extraction agent for nuclear iste treatment.
| Cell Experiment | |
|---|---|
| Cell lines | Desulfovibrio alaskensis |
| Preparation method | The protonophore 3,3,4,5-tetrachlorosalicylanilide (TCS, 5 µM or 20 µM), or the sodium-specific ionophore N,N,N′,N′-Tetracyclohexyl-1,2-phenylenedioxydiacetamide (ETH2120, 20 µM) were added to media to test their effects on growth. |
| Concentrations | 20 µM |
| Incubation time | 24 h |
| Animal Experiment | |
|---|---|
| Animal models | |
| Formulation | |
| Dosages | |
| Administration | |
| Molecular Weight | 552.79 |
| Formula | C34H52N2O4 |
| CAS Number | 81686-22-8 |
| Solubility (25°C) | 10 mM in DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Wang L, et al. PeerJ. The role of Rnf in ion gradient formation in Desulfovibrio alaskensis.
| Related Sodium Channel Products |
|---|
| Riluzole
Rilutek is a sodium channel protein inhibitor and a new mental compound, which has anticonvulsant, hypnotic, antianxiety, antiischemia and anesthesia properties. Riluzole belongs to the family of use-dependent Na+ channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM. |
| A-803467
A-803467 is a potent and selective Nav1.8 sodium channel blocker that potently blocks tetrodotoxin-resistant currents (IC50 = 140 nM). |
| Oxcarbazepine
Oxcarbazepine is an anticonvulsant and mood-stabilizing compound. |
| Ambroxol hydrochloride
AmbroxolHCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 μM. |
| Camostat mesylate
Camostat mesylate is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trpsin, prostasin and matriptase. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
