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Esculin

Cat. No. M14175

All AbMole products are for research use only, cannot be used for human consumption.

Esculin Structure
Size Price Availability Quantity
500mg USD 50 In stock
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Quality Control & Documentation
Biological Activity

Esculin, a fluorescent coumarin glucoside, is an active ingredient of ash bark. Esculin ameliorates cognitive impairment in experimental diabetic nephropathy (DN), and exerts anti‑oxidative stress and anti‑inflammatory effects, via the MAPK signaling pathway.

Chemical Information
Molecular Weight 340.28
CAS Number 531-75-9
Solubility (25°C) DMSO 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Chun-Xiao Li, et al. The pharmacological and pharmacokinetic properties of esculin: A comprehensive review

[2] Xi-Ding Yang, et al. Esculin protects against methionine choline-deficient diet-induced non-alcoholic steatohepatitis by regulating the Sirt1/NF- κB p65 pathway

[3] Lisha Hao, et al. Highly efficient whole-cell biosynthesis and cytotoxicity of esculin esters

[4] M Mo, et al. [Esculin inhibits proliferation of triple negative breast cancer cells by down-regulating FBI-1]

[5] R S Serralha, et al. Esculin reduces P2X7 and reverses mitochondrial dysfunction in the renal cortex of diabetic rats

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Keywords: Esculin supplier, p38 MAPK, inhibitors, activators

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