All AbMole products are for research use only, cannot be used for human consumption.
Escin IA, a triterpenoid saponin isolated from horse chestnut, inhibits HIV-1 protease with IC50 value of 35 μM. Escin IA has anti-metastasis activity of triple negative breast cancer, and its mechanism includes down-regulation of LOXL expression and inhibition of epithelial mesenchymal transformation.
| Molecular Weight | 1131.26 |
| Formula | C55H86O24 |
| CAS Number | 123748-68-5 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage | 4°C, protect from light, dry, sealed |
[3] Xiu-Jun Wu, et al. Pharmacokinetics of escin Ia in rats after intravenous administration
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