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Erianin

Cat. No. M13464

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Erianin Structure
Size Price Availability Quantity
1mg USD 20 In stock
5mg USD 50 In stock
10mg USD 80 In stock
20mg USD 120 In stock
50mg USD 240 In stock
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Quality Control & Documentation
Biological Activity

Erianin, a bibenzyl analog isolated from Dendrobium bulbosum, is also a PD-L1 inhibitor that exhibits potential antitumor activity in a variety of malignant tumors.Erianin regulates a variety of cancer-associated pathways in vitro and in vivo, including apoptosis, cell-cycle arrest, invasion, migration, and autophagy. In addition, Erianin inhibits indoleamine-2,3-dioxygenase (IDO)-induced tumor angiogenesis.

Chemical Information
Molecular Weight 318.36
CAS Number 95041-90-0
Solubility (25°C) DMSO 90 mg/mL
Storage 2-8°C, protect from light
References

[1] Yu Xiang, et al. Front Pharmacol. Natural Product Erianin Inhibits Bladder Cancer Cell Growth by Inducing Ferroptosis via NRF2 Inactivation

[2] Yan Wang, et al. J Ethnopharmacol. Erianin, the main active ingredient of Dendrobium chrysotoxum Lindl, inhibits precancerous lesions of gastric cancer (PLGC) through suppression of the HRAS-PI3K-AKT signaling pathway as revealed by network pharmacology and in vitro experimental verificati䲧

[3] Yonggang Xu, et al. Biosci Rep. Erianin induces triple-negative breast cancer cells apoptosis by activating PI3K/Akt pathway

[4] Peng Chen, et al. Signal Transduct Target Ther. Erianin, a novel dibenzyl compound in Dendrobium extract, inhibits lung cancer cell growth and migration via calcium/calmodulin-dependent ferroptosis

[5] Tianyu Zhang, et al. FASEB J. Erianin alleviates diabetic retinopathy by reducing retinal inflammation initiated by microglial cells via inhibiting hyperglycemia-mediated ERK1/2-NF-κB signaling pathway

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Keywords: Erianin supplier, PD-1/PD-L1, inhibitors, activators

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