All AbMole products are for research use only, cannot be used for human consumption.
For this product's availability, delivery time and price, please email inquiry@abmole.com directly or click the "Inquiry Now" button below.
ERAS-4001 is a pan-KRAS inhibitor, it has potent antitumor activities and significantly inhibits the proliferation of wild-type and mutant (such as KRASG12D, KRASG12V and KRASG12C) cancer cells. ERAS-4001 binds to both wild-type KRAS and the KRAS G12X mutant, and inhibits downstream signalling by KRAS via effector proteins such as the RAF protein family.
| Molecular Weight | 743.19 |
| Formula | C36H39ClF4N8O3 |
| CAS Number | 3024878-19-8 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Ras Products |
|---|
| ZCL278
ZCL278 is a selective Cdc42 GTPase inhibitor with Kd of 11.4 μM. |
| Kobe0065
Kobe0065 is a novel and effective small-molecule compound inhibiting Ras–Raf interaction by SBDD, exhibits potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 μM. |
| K-Ras(G12C) inhibitor 9
K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C). |
| 6H05 trifluoroacetate
6H05 is a selective and allosteric inhibitor of oncogenic K-Ras(G12C). |
| Salirasib
Salirasib is a potent competitive prenylated protein methyltransferase (PPMTase) inhibitor with Ki of 2.6 μM, which inhibits Ras methylation. Phase 2. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
