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ER 27319 maleate is a selective inhibitor of Syk kinase. Inhibits tyrosine phosphorylation of Syk initiated by the engagement of FcεRI in rat and human mast cells. Results in the abrogation of degranulation, TNF-α production (IC50 = 10 μM) and other related signaling events.
| Molecular Weight | 396.17 |
| Formula | C18H20N2O.C4H4O4 |
| CAS Number | 1204480-26-1 |
| Solubility (25°C) | Water 29.71 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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