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Erythropoietin (EPO) is a glycoprotein hormone known primarily for its role in erythropoiesis, which is responsible for stimulating the proliferation and differentiation of erythroid progenitor cells. Cfu-e cells can differentiate into red blood cells only in the presence of EPO. The physiological levels of EPO in adult mammals are mainly maintained by the kidneys, while in fetal or newborn mammals, EPO levels are maintained by the liver. EPO also performs a variety of non-hematopoietic activities, including vascularization and smooth muscle proliferation, neuroprotection during hypoxia, and stimulation of certain B cells.
DNA sequence encoding human EPO (Ala28-Arg193) expressed.
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells, the ED50 is < 1.0 ng/ml, corresponding to a specific activity of > 1.0 × 106 units/mg.
Accession: P01588
Endotoxin < 0.2 EU/µg
Apparent Molecular Weight: 26~36 kDa, reducing conditions
Lyophilized from sterile PBS, pH 7.4.
Nucleic Acids Res. 2022 Aug 12;50(14):7938-7958.
HDAC1 and PRC2 mediate combinatorial control in SPI1/PU.1-dependent gene repression in murine erythroleukaemia
Recombinant Human EPO Protein (CHO) purchased from AbMole
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml. |
| Storage | Stored at -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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Products are for research use only. Not for human use. We do not sell to patients.
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