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Epaminurad (UR-1102) is an orally active, potent and selective URAT1 (urate transporter 1) inhibitor, with a Ki of 0.057 μM. Epaminurad quite modestly inhibits OAT1 and OAT3 (organic anion transporter). Epaminurad is a uricosuric agent. Epaminurad can be used for gout and hyperuricemia research.
| Molecular Weight | 414.05 |
| Formula | C14H10Br2N2O3 |
| CAS Number | 1198153-15-9 |
| Form | Solid |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related URAT1 Products |
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| Lesinurad
Lesinurad is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 µM, respectively. |
| Verinurad
Verinurad, also known as RDEA3170, is an organic anion transporter URAT1 inhibitor with an IC50 of 25 nM. |
| Dotinurad
Dotinurad is a potent selective urate reabsorption inhibitor. Dotinurad inhibits Urate Transporter 1 (URAT1), IC50 value is 37.2 nM. Dotinurad is used as a uric acid-enhancing excretor. |
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Products are for research use only. Not for human use. We do not sell to patients.
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