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Enzalutamide carboxylic acid

Cat. No. M14322

All AbMole products are for research use only, cannot be used for human consumption.

Enzalutamide carboxylic acid Structure
Synonym:

MDV3100 carboxylic acid

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Quality Control & Documentation
Biological Activity

Enzalutamide carboxylic acid (MDV3100 carboxylic acid) is an inactive metabolite of Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist.

Chemical Information
Molecular Weight 451.39
CAS Number 1242137-15-0
Solubility (25°C) DMSO 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Keith T Schmidt, et al. Resistance to second-generation androgen receptor antagonists in prostate cancer

[2] Mathieu Roumigui, et al. Apalutamide, darolutamide and enzalutamide in nonmetastatic castration-resistant prostate cancer: a meta-analysis

[3] Yuanyuan Wang, et al. Mechanisms of enzalutamide resistance in castration-resistant prostate cancer and therapeutic strategies to overcome it

[4] Tomasz M Beer, et al. Enzalutamide in Men with Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer: Extended Analysis of the Phase 3 PREVAIL Study

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Keywords: Enzalutamide carboxylic acid, MDV3100 carboxylic acid supplier, inhibitors, activators

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