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EN6

Cat. No. M10277

All AbMole products are for research use only, cannot be used for human consumption.

EN6 Structure
Synonym:

ABM-4739

Size Price Availability Quantity
1mg USD 40 In stock
5mg USD 90 In stock
10mg USD 145 In stock
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Quality Control & Documentation
Biological Activity

EN6-mediated ATP6V1A modification decouples the v-ATPase from the Rags, leading to inhibition of mTORC1 signaling, increased lysosomal acidification and activation of autophagy.

Chemical Information
Molecular Weight 368.34
Formula C19H14F2N4O2
CAS Number 1808714-73-9
Form Solid
Solubility (25°C) DMSO 4 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Clive Yik-Sham Chung, et al. Nat Chem Biol. Covalent targeting of the vacuolar H +-ATPase activates autophagy via mTORC1 inhibition

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Keywords: EN6, ABM-4739 supplier, Autophagy, inhibitors, activators

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