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Emodin

Cat. No. M7790

All AbMole products are for research use only, cannot be used for human consumption.

Emodin Structure
Synonym:

Frangula emodin

Size Price Availability Quantity
50mg USD 45 In stock
100mg USD 65 In stock
200mg USD 85 In stock
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Quality Control & Documentation
Biological Activity

Emodin is an anti-SARS-CoV compound that blocks the interaction between the SARS-coronavirus spike protein and angiotensin converting enzyme 2 (ACE2). Emodin inhibited casein kinase 2 (CK2) and 11β-HSD1. Emodin can also induce necrotic apoptosis of glioma U251 cells and inhibit U251 cell proliferation by targeting the TNF/RIPK1/RIPK3 signaling pathway.


Chemical Information
Molecular Weight 270.24
Formula C15H10O5
CAS Number 518-82-1
Solubility (25°C) DMSO ≥ 9 mg/mL (Need ultrasonic and warming)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Xinxing Li, et al. BMC Cancer. Emodin enhances cisplatin-induced cytotoxicity in human bladder cancer cells through ROS elevation and MRP1 downregulation

[2] Jie-yu Xing, et al. PLoS One. Antitumor Effects and Mechanism of Novel Emodin Rhamnoside Derivatives against Human Cancer Cells In Vitro

[3] Tin-Yun Ho, et al. Antiviral Res. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 interaction

[4] H Yim, et al. Planta Med. Emodin, an anthraquinone derivative isolated from the rhizomes of Rheum palmatum, selectively inhibits the activity of casein kinase II as a competitive inhibitor

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Keywords: Emodin, Frangula emodin supplier, Casein Kinase, inhibitors, activators

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