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Emedastine

Cat. No. M20515

All AbMole products are for research use only, cannot be used for human consumption.

Emedastine Structure

Price and Availability

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Quality Control & Documentation
Biological Activity

Emedastine is a potent, high affinity histamine H1-receptor-selective antagonist with Ki of 1.3 ±0.1 nM for H1-receptors while considerably weaker at H2- (K1 = 49,067 ± 11,113 nM) and H3-receptors (Ki = 12,430 ± 1,282 nM).

Chemical Information
Molecular Weight 302.41
Formula C17H26N4O
CAS Number 87233-61-2
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jumpei Saito, et al. Breastfeed Med. Emedastine During Pregnancy and Lactation: Emedastine Levels in Maternal Serum, Cord Blood, Breast Milk, and Neonatal Serum

[2] No authors listed. Emedastine

[3] Maulina Sharma, et al. Cochrane Database Syst Rev. H1-antihistamines for chronic spontaneous urticaria

[4] Hiroyuki Murota, et al. Expert Opin Pharmacother. Emedastine difumarate: a review of its potential ameliorating effect for tissue remodeling in allergic diseases

[5] U Herranz, et al. Int J Clin Pharmacol Ther. Emedastine-ketoconazole: pharmacokinetic and pharmacodynamic interactions in healthy volunteers

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Keywords: Emedastine supplier, Histamine Receptor, inhibitors, activators

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