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Emactuzumab

Cat. No. M24683

All AbMole products are for research use only, cannot be used for human consumption.

Emactuzumab Structure
Synonym:

RG 7155; RO 5509554

Price and Availability

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Quality Control & Documentation
Biological Activity

Emactuzumab(RG 7155) is a specific monoclonal antibody that inhibits colonystimulating factor 1 receptor (CSF1R) activation. Emactuzumab has high affinity for CSF-1R with Ki value of 0.2 nM to blocks CSF-1R dimerization. Emactuzumab can be used for the research of several diseases, such as diffuse-type tenosynovial giant cell tumour (dt-GCT) .

Chemical Information
CAS Number 1448221-67-7
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Emanuela Palmerini, et al. Curr Opin Oncol. Treatment updates on tenosynovial giant cell tumor

[2] Leon P Pradel, et al. Mol Cancer Ther. Macrophage Susceptibility to Emactuzumab (RG7155) Treatment

[3] Carola H Ries, et al. Cancer Cell. Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy

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  Catalog
Abmole Inhibitor Catalog




Keywords: Emactuzumab, RG 7155; RO 5509554 supplier, CSF-1R (c-Fms), inhibitors, activators

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