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EMAC10101d 

Cat. No. M29708

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EMAC10101d  Structure

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Quality Control & Documentation
Biological Activity

EMAC10101d is a potent and selective toward hCA II inhibitor, with a Ki of 8.1 nM.

Chemical Information
Molecular Weight 428.36
Formula C17H15Cl2N3O2S2
CAS Number 2561476-24-0
Form Solid
Solubility (25°C) DMSO 62.5 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Rita Meleddu, et al. ACS Med Chem Lett. New Dihydrothiazole Benzensulfonamides: Looking for Selectivity toward Carbonic Anhydrase Isoforms I, II, IX, and XII

Related Carbonic Anhydrase Products
Benzthiazide

Benzthiazide is a thiazide diuretic, promoting water loss from the body.

Brinzolamide

Brinzolamide (Brinzolamide) is a potent and effective carbonic anhydrase-II inhibitor with an IC50 of 3.19 nM.In addition, Brinzolamide reduces intraocular aqueous humor production in the eye and may be used in studies related to glaucoma.

Ethoxzolamide

Ethoxzolamide is an inhibitor of the metalloenzyme carbonic anhydrase, which inhibits hCA I, hCA II, hCA IV, hCA VI and hCA VII with Ki of 25 nM, 8 nM, 93 nM, 43 nM and 0.8 nM, respectively.

Fluorometholone Acetate

Fluorometholone Acetate is a synthetic corticosteroid and a potent carbonic anhydrase (CA) inhibitor with IC50s of 2.18 μM for hCA-I and 17.5 μM for hCA-II. It has anti-inflammatory activity and may be used in studies related to steroid-responsive ocular inflammation.

Methazolamide

Methazolamide is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively.

  Catalog
Abmole Inhibitor Catalog




Keywords: EMAC10101d  supplier, Carbonic Anhydrase, inhibitors, activators

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