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Eliapixant

Cat. No. M10814

All AbMole products are for research use only, cannot be used for human consumption.

Eliapixant Structure
Synonym:

BAY 1817080

Price and Availability

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Quality Control & Documentation
Biological Activity

Eliapixant (BAY 1817080) is an effective and selective P2X3 receptor antagonist.IC50 The value is 8 nM. Eliapixant can be used in the study of refractory chronic cough.

Chemical Information
Molecular Weight 478.49
Formula C22H21F3N4O3S
CAS Number 1948229-21-7
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Adam J Davenport, et al. Sci Rep. Eliapixant is a selective P2X3 receptor antagonist for the treatment of disorders associated with hypersensitive nerve fibers

[2] Alyn Morice, et al. Eur Respir J. Eliapixant (BAY 1817080), a P2X3 receptor antagonist, in refractory chronic cough: a randomised, placebo-controlled, crossover phase 2a study

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Abmole Inhibitor Catalog




Keywords: Eliapixant, BAY 1817080 supplier, P2 Receptor, inhibitors, activators

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