All AbMole products are for research use only, cannot be used for human consumption.
EGF protein, Human (E. coli) （High Efficiency ） is an important epidermal growth factor that stimulates epidermal cell proliferation and can be applied to the study of wound healing. EGF signals through the EGF receptor (EGFR) also known as erbB1, is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor). EGF-receptor binding results in cellular proliferation, differentiation, and survival. The biological effects of salivary EGF include healing of oral and gastroesophageal ulcers, inhibition of gastric acid secretion, stimulation of DNA synthesis as well as mucosal protection from intraluminal injurious factors such as gastric acid, bile acids, pepsin, and trypsin and to physical, chemical and bacterial agents.
Calculated by the dose-dependant proliferation of murine BALB/c 3T3 cells, the ED50 is less than 0.2 ng/ml, corresponding to a specific activity of 5.0 × 106 IU/ mg.
| Solubility (25°C) | Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[5] F Berger, et al. Neurochirurgie. [The EGF receptor pathway in human cerebral tumors]
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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