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Eftozanermin alfa

Cat. No. M24821

All AbMole products are for research use only, cannot be used for human consumption.

Eftozanermin alfa Structure
Synonym:

ABBV-621

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Quality Control & Documentation
Biological Activity

Eftozanermin alfa (ABBV-621) is a second-generation tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) agonist. Eftozanermin alfa induces apoptosis in tumor cells by activation of death receptors 4/5. Eftozanermin alfa can be used for the research of multiple solid and heme malignancies.

Chemical Information
CAS Number 1820660-69-2
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Francesca Di Cristofano, et al. Biochem Soc Trans. Therapeutic targeting of TRAIL death receptors

[2] Darren C Phillips, et al. Cancer Res. Hexavalent TRAIL Fusion Protein Eftozanermin Alfa Optimally Clusters Apoptosis-Inducing TRAIL Receptors to Induce On-Target Antitumor Activity in Solid Tumors

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Keywords: Eftozanermin alfa, ABBV-621 supplier, Apoptosis, inhibitors, activators

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