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Ecopipam

Cat. No. M27812

All AbMole products are for research use only, cannot be used for human consumption.

Ecopipam Structure
Synonym:

SCH 39166

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Quality Control & Documentation
Biological Activity

Ecopipam (SCH 39166) is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam shows more than 40-flod selectivity over D2, D4, 5-HT, and α2a receptor (Ki=0.98, 5.52, 0.08, and 0.73 μM, respectively). Ecopipam can be used for the research of schizophrenia and obesity.

Chemical Information
Molecular Weight 313.82
Formula C19H20ClNO
CAS Number 112108-01-7
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Donald L Gilbert, et al. Pediatrics. Ecopipam for Tourette Syndrome: A Randomized Trial

[2] Jessica Frey, et al. Curr Neurol Neurosci Rep. Tourette Syndrome Treatment Updates: a Review and Discussion of the Current and Upcoming Literature

[3] Kallol K Set, et al. Curr Probl Pediatr Adolesc Health Care. Tourette syndrome in children: An update

[4] Andrew Billnitzer, et al. Neurotherapeutics. Current Management of Tics and Tourette Syndrome: Behavioral, Pharmacologic, and Surgical Treatments

[5] Gerald A Maguire, et al. Ann Clin Psychiatry. Ecopipam as a pharmacologic treatment of stuttering

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Keywords: Ecopipam, SCH 39166 supplier, Dopamine Receptor, inhibitors, activators

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