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Econazole nitrate (Spectazole) is an imidazole class antifungal medication. Econazole nitrate (Spectazole) is used to treat skin infections such as athlete’s foot, tinea, pityriasis versicolor, ringworm, and jock itch. The in vitro activity spectrum of econazole nitrate (Spectazole) is very broad: the dermatophytes, the yeasts, the dimorphic fungi, the aspergilli, the mycetoma causing agents and the Gram-positive bacteria being most sensitive. Guinea-pigs infected with T. mentagrophytes, M. canis or C. albicans and treated topically or orally with econazole, were cured. In each of these tests the activity of econazole was compared with that of different reference drugs. Vaginal candidiasis in rats was cured after oral administration of econazole.
| Molecular Weight | 444.7 |
| Formula | C18H15Cl3N2O.HNO3 |
| CAS Number | 24169-02-6 |
| Form | Solid |
| Solubility (25°C) | DMSO 80 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Alan B Fleischer Jr, et al. Econazole Nitrate Foam 1% Improves the Itch of Tinea Pedis
[3] Irina Vennewald, et al. Otomycosis: Diagnosis and treatment
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