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Echistatin TFA

Cat. No. M10636

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Echistatin TFA Structure
Size Price Availability Quantity
1mg USD 1000 In stock
5mg USD 2500 In stock
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Quality Control & Documentation
Biological Activity

Echistatin TFA is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorption in culture. Echistatin is a potent antagonist of αIIbβ3, αvβ3 and α5β1. Echistatin TFA is the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms.

Chemical Information
Molecular Weight 5531.02
Formula C219H342F3N71O76S9
CAS Number 154303-05-6 (free base)
Solubility (25°C) Water 45 mg/mL (May need ultrasonic)
Storage -20°C, dry, sealed
References

[1] I Wierzbicka-Patynowski, et al. J Biol Chem . Structural requirements of echistatin for the recognition of alpha(v)beta(3) and alpha(5)beta(1) integrins

[2] C C Kumar, et al. J Pharmacol Exp Ther . Biochemical characterization of the binding of echistatin to integrin alphavbeta3 receptor

[3] J Musial, et al. Circulation . Inhibition of platelet adhesion to surfaces of extracorporeal circuits by disintegrins. RGD-containing peptides from viper venoms

[4] M Sato, et al. J Cell Biol . Echistatin is a potent inhibitor of bone resorption in culture

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Keywords: Echistatin TFA supplier, Integrin, inhibitors, activators

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