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ECBN HCL

Cat. No. M6132

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ECBN HCL Structure
Size Price Availability
10mg USD 200 4-7 Days
50mg USD 420 4-7 Days
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Quality Control & Documentation
Biological Activity

ECBN biosynthesis cluster Ani in the genome of the echinocandin B producer strain A. nidulans NRRL 8112. ECBN belongs to lipopeptide antifungal antibiotic bearing five types of direct precursor amino acids including proline, ornithine, tyrosine, threonine, and leucine. ECBN obtained by the fermentation of Aspergillus nidulans and Aspergillus rugulosus, is known as one of the natural cyclic hexapeptides that have a linoleoyl side chain, which inhibits a crucial enzyme in fungal cell wall biosynthesis, β-(1,3)-d-glucan synthase.

Chemical Information
Molecular Weight 834.27
Formula C34H51N7O15.HCl
CAS Number 1029890-89-8
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Hu ZC, et al. Appl Biochem Biotechnol. Enhancement of Echinocandin B Production by a UV- and Microwave-Induced Mutant of Aspergillus nidulans with Precursor- and Biotin-Supplying Strategy.

[2] Shao L, et al. Appl Environ Microbiol. Efficient bioconversion of echinocandin B to its nucleus by overexpression of deacylase genes in different host strains.

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Keywords: ECBN HCL supplier, inhibitors, activators

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