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EC5026 (BPN-19186) is a first-in-class, potent and orally active soluble inhibitor of Epoxide Hydrolase (sEH). EC5026 has the potential to relieve pain by stabilizing natural analgesic and anti-inflammatory mediators. In vivo, EC5026 (BPN-19186) has already shown efficacy for treating pain with no apparent adverse or addictive effects in laboratory animals and relieving naturally occurring pain in dogs, cats and horses.
| Molecular Weight | 405.39 |
| Formula | C18H23F4N3O3 |
| CAS Number | 1809885-32-2 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 100 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Epoxide Hydrolase Products |
|---|
| Pentyl Chloroformate
Certain substituted caprolactam carbonates and ethers, compound compositions containing them and their use in the study of tumors. |
| TPPU
TPPU is a potent soluble epoxide hydrolase inhibitor; orally bioavailable and brain penetrant. |
| AUDA
AUDA is a potent inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 18 nM and 69 nM for the mouse sEH and human sEH, respectively. AUDA has anti-inflammatory activity that reduces the protein expression of MMP-9, IL-1β, TNF-α and TGF-β. |
| Valpromide
Valpromide (VPD) is a derivative of valproic acid (VPA) and is used as an antiepileptic drug. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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