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E7090 

Cat. No. M28710

All AbMole products are for research use only, cannot be used for human consumption.

E7090  Structure
Synonym:

Tasurgratinib

Price and Availability

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Quality Control & Documentation
Biological Activity

E7090 is an orally available, potent, and selective FGFR inhibitor with IC50s of 0.71 nM, 0.50 nM, 1.2 nM, and 120 nM for FGFR1/FGFR2/FGFR3/FGFR4, respectively.

Chemical Information
Molecular Weight 587.67
Formula C32H37N5O6
CAS Number 1622204-21-0
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yoshiki Asakawa, et al. J Pharm Biomed Anal. A validated UPLC-MS/MS assay of E7090, a novel selective inhibitor of fibroblast growth factor receptors, in human plasma and urine

[2] Gregory D Sloop, et al. Cureus. The Role of Blood Viscosity in Infectious Diseases

[3] Saori Watanabe Miyano, et al. Mol Cancer Ther. E7090, a Novel Selective Inhibitor of Fibroblast Growth Factor Receptors, Displays Potent Antitumor Activity and Prolongs Survival in Preclinical Models

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  Catalog
Abmole Inhibitor Catalog




Keywords: E7090 , Tasurgratinib supplier, FGFR, inhibitors, activators

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