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DTNB (Ellman's Reagent) is a chemical used for quantifying the amount or concentration of sulfhydryl groups. It is often used to detect free sulfhydryl groups. DTNB is also an allosteric inhibitor of dengue virus protease (NS2B-NS3Pro) and Streptomyces protease.
| Molecular Weight | 396.35 |
| Formula | C14H8N2O8S2 |
| CAS Number | 69-78-3 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] Joshua B Owen, et al. Methods Mol Biol. Measurement of oxidized/reduced glutathione ratio
[4] M R Toon, et al. Biochim Biophys Acta. Binding of DTNB to band 3 in the human red cell membrane
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