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DS12881479 is a potent and selective Mnk1 inhibitor with an IC50 value of 21 nM.
| Molecular Weight | 301.41 |
| Formula | C16H19N3OS |
| CAS Number | 2373065-59-7 |
| Form | Solid |
| Solubility (25°C) | DMSO 150 mg/mL |
| Storage | Powder -20°C |
| Related MNK Products |
|---|
| CGP 57380
CGP 57380 is potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases. |
| Tomivosertib (eFT-508)
Tomivosertib (eFT-508) is a potent and selective MNK1/2 inhibitor with IC50s of 2.4 nM and 1 nM, respectively. It potentially results in decreased tumor cell proliferation and tumor growth. |
| SLV-2436
SLV-2436 (SEL201-88) is a novel ATP-competitive inhibitor of MNK1 and MNK2 with IC50 of 10.8 nM and 5.4 nM, respectively. |
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