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Droloxifene, a Tamoxifen derivative, is an orally active and selective estrogen receptor modulator. Droloxifene shows antiestrogenic and anti-implantation effects. Droloxifene induces p53 expression and apoptosis in MCF-7 cells. Droloxifene prevents bone loss in ovariectomized rats .
| Molecular Weight | 387.51 |
| CAS Number | 82413-20-5 |
| Solubility (25°C) | DMSO 50 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] No authors listed. Droloxifene
[4] M Hasmann, et al. Preclinical data for Droloxifene
[5] U Eppenberger, et al. Pharmacologic and biologic properties of droloxifene, a new antiestrogen
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