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Drofenine hydrochloride

Cat. No. M14546

All AbMole products are for research use only, cannot be used for human consumption.

Drofenine hydrochloride Structure
Synonym:

Hexahydroadiphenine hydrochloride

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Quality Control & Documentation
Biological Activity

Drofenine hydrochloride is a potent competitive inhibitor of BChE, and the ki values of Drofenine is calculated to be 3 uM. IC50 value: 3 uM (ki) Target: BChE Benactyzine is widely used anticholinergic drugs, acts on smooth muscle to stop muscle spasms.

Chemical Information
Molecular Weight 353.93
CAS Number 548-66-3
Solubility (25°C) DMSO ≥ 75 mg/mL
Water ≥ 33.3 mg/mL
Storage 2-8°C, dry, sealed
References

[1] G Facchini, et al. Simultaneous determination of hydrochloride salts of adiphenine, diphenhydramine, ethyldiphenacetate, drofenine and promazine by ion-pair HPLC

[2] E Pawelczyk, et al. Studies on kinetics of degradation of drugs. XIX. Thermic degradation of aminophenazone (AP), allobarbital (AB), cycloadiphenine hydrochloride (CAD) mixture in cetyl phtalate medium

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Keywords: Drofenine hydrochloride, Hexahydroadiphenine hydrochloride supplier, AChR/AChE, inhibitors, activators

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