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DR2313

Cat. No. M8325

All AbMole products are for research use only, cannot be used for human consumption.

DR2313 Structure

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Quality Control & Documentation
Biological Activity

DR2313 is a PARP-1; PARP-2 inhibitor (Ki = 0.23 mM). DR2313 has neuroprotective effects in both in vivo and in vitro ischemic models, and reduces cortical infarct volume in focal ischemia in rats.

Chemical Information
Molecular Weight 182.24
Formula C8H10N2OS
CAS Number 284028-90-6
Solubility (25°C) Water: ≥2 mg/mL (warmed)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Wei Qiu, et al. Insights into the binding of PARP inhibitors to the catalytic domain of human tankyrase-2

[2] Hidemitsu Nakajima, et al. A newly synthesized poly(ADP-ribose) polymerase inhibitor, DR2313 [2-methyl-3,5,7,8-tetrahydrothiopyrano[4,3-d]-pyrimidine-4-one]: pharmacological profiles, neuroprotective effects, and therapeutic time window in cerebral ischemia in rats

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Abmole Inhibitor Catalog




Keywords: DR2313 supplier, inhibitors, activators

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