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DQ-BSA-Red is a fluorescent lysosomal activity molecular probe based on bovine serum albumin (BSA). The BSA molecule undergoes multi-site high-concentration labeling with a red fluorescent dye. Due to the high concentration of distributed fluorescent probes, the labeled BSA molecule exhibits significant fluorescence self-quenching. When degraded within functional, active lysosomes, DQ-BSA-Red generates BSA protein fragments. These fragments possess isolated fluorophores, thereby releasing the dye from self-quenching and emitting bright fluorescence within cells. Dysfunctional lysosomes, however, cannot degrade the BSA protein, resulting in significantly reduced or nearly absent fluorescence signals.
| Solubility (25°C) | Water/PBS: 1 mg/mL |
| Storage |
-20°C, protect from light -80°C, protect from light for long term storage |
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