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DPPE hydrochloride

Cat. No. M7751

All AbMole products are for research use only, cannot be used for human consumption.

DPPE hydrochloride Structure

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Quality Control & Documentation
Biological Activity

DPPE is a potent, selective ligand of the microsomal anti-estrogen binding site. DPPE is a tamoxifen derivataive that binds with high affinity to the anti-estrogen binding site, but unlike tamoxifen, does not bind to the estrogen receptor. DPPE sensitizes MDR tumor cells to chemotherapy and also inhibits histamine binding at the intracellular histamine site.

Chemical Information
Molecular Weight 319.87
Formula C19H25NO·HCl
CAS Number 92981-78-7
Solubility (25°C) Water: 16 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Matheus Elias Rosa, et al. Interaction of isolinderanolide E obtained from Nectandra oppositifolia with biomembrane models

[2] Lei Liu, et al. Co-Delivery of Triptolide and Curcumin for Ovarian Cancer Targeting Therapy via mPEG-DPPE/CaP Nanoparticle

[3] L J Brandes, et al. Study of the in-vivo antioestrogenic action of N,N-diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine HCl (DPPE), a novel intracellular histamine antagonist and antioestrogen binding site ligand

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Keywords: DPPE hydrochloride supplier, inhibitors, activators

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