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Dp44mT is an iron chelator that works as a selective anticancer agent. As other iron chelators it can serve as a therapeutic adjunct to doxorubicin treatment. Additionally Dm44mT possess DNA-damaging activity. It appears that that activity is mediated by top2a inhibition.
| Molecular Weight | 285.37 |
| Formula | C14H15N5S |
| CAS Number | 152095-12-0 |
| Solubility (25°C) | DMSO: ≥5 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[5] C K Holley, et al. Fabrication and Optimization of Dp44mT-Loaded Nanoparticles
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