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Dosimertinib

Cat. No. M21108

All AbMole products are for research use only, cannot be used for human consumption.

Dosimertinib Structure

Price and Availability

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Quality Control & Documentation
Biological Activity

Dosimertinib is a highly potent, selective, orally effective EGFR inhibitor for the study of non-small cell lung cancer.

Chemical Information
Molecular Weight 504.64
Formula C28H28D5N7O2
CAS Number 2403760-70-1
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yvette N Lamb. Target Oncol. Osimertinib: A Review in Previously Untreated, EGFR Mutation-Positive, Advanced NSCLC

[2] Ying Cheng, et al. Target Oncol. Osimertinib Versus Comparator EGFR TKI as First-Line Treatment for EGFR-Mutated Advanced NSCLC: FLAURA China, A Randomized Study

[3] Sabine Schmid, et al. Lung Cancer. Mechanisms of osimertinib resistance and emerging treatment options

[4] Alessandro Leonetti, et al. Br J Cancer. Resistance mechanisms to osimertinib in EGFR-mutated non-small cell lung cancer

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Keywords: Dosimertinib supplier, EGFR/HER2, inhibitors, activators

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