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DMG-PEG 2000 is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles.
| Formula | (C2H4O)nC32H62O5 |
| CAS Number | 160743-62-4 |
| Solubility (25°C) | DMSO 90 mg/mL (ultrasonic and warming) Ethanol 90 mg/mL (Need ultrasonic) Water 15 mg/mL (Need ultrasonic) |
| Storage | -20°C, protect from light, dry, sealed |
[3] S Moein Moghimi. Mol Ther. Allergic Reactions and Anaphylaxis to LNP-Based COVID-19 Vaccines
[4] Weiyu Zhao, et al. Cell Mol Bioeng. Lipid Polymer Hybrid Nanomaterials for mRNA Delivery
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| Hexadimethrine bromide
Hexadimethrine bromide can be used to transfect mammalian cells with DNA. It can be used to increase the efficiency of lipofection transfections.In addition, Polybrene can be used as a promoter in virus-mediated gene therapy assays and in studies of gene transfer. |
| DOTAP chloride
DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids. |
| DSPE-PEG-2K-Amine
DSPE-PEG-2K-Amine is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE, used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents. |
| DOPE
DOPE (1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine) forms heterogenous liposomes with N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium methylsulfate (DOTAP), which are used as delivery vehicles for therapeutic agents. |
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