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DJ001 is a highly specific, selective and non-competitive protein tyrosine phosphatase-σ (PTPσ) inhibitor,IC50 is 1.43 μM. DJ001 has no inhibitory activity against other phosphatases and only moderate inhibitory activity against protein phosphatase 5. DJ001 Promotes hematopoietic stem cell regeneration.
| Molecular Weight | 268.27 |
| Formula | C15H12N2O3 |
| CAS Number | 2161305-12-8 |
| Solubility (25°C) | DMSO ≥ 200 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Yurun Zhang, et al. Nat Commun. PTPσ inhibitors promote hematopoietic stem cell regeneration
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